Toronto scientists are behind a groundbreaking discovery that links a
defective gene in humans to autoimmune diseases like rheumatoid
arthritis, diabetes, and lupus. The research, led by Mount Sinai's Dr.
Katherine Siminovitch, is an important first step in finding new treatments for a number of often debilitating diseases.
"For a period of five years, the researchers have tried to figure out
as to how the mutant gene PTPN22 increases the risk for rheumatoid
arthritis, type 1 diabetes, lupus, Graves disease and other autoimmune
disorders."
"Dr. Katherine Siminovitch, a Senior Investigator at the Samuel
Lunenfeld Research Institute at Mount Sinai Hospital and a University
of Toronto Professor said, "Our findings are particularly exciting
because the study sets a new precedent for studying arthritis and other
autoimmune disorders".
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