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UofT researchers crack 'splicing code,' solve a mystery underlying biological complexity

As reported on Physorg.com University of Toronto researchers have discovered the hidden code within DNA that explains how a small number of human genes can provide the directives for organs as complicated as the human brain. The UofT scientists presented their groundbreaking discovery on May 6th in a paper published in the Nature journal entitled "Deciphering the Splicing Code".

"In a paper published on May 6 in the journal Nature entitled "Deciphering the Splicing Code," a research team led by Professors Brendan Frey and Benjamin Blencowe of the University of Toronto describes how a hidden code within DNA explains one of the central mysteries of genetic research - namely how a limited number of human genes can produce a vastly greater number of genetic messages. The discovery bridges a decade-old gap between our understanding of the genome and the activity of complex processes within cells, and could one day help predict or prevent diseases such as cancers and neurodegenerative disorders."

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original source Physorg.com
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